What causes fever
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Last updated: April 4, 2026
Key Facts
- Fever is a temporary increase in body temperature above the normal range of 98.6°F (37°C).
- The most common cause of fever is infection, accounting for over 80% of cases.
- Viruses are responsible for the majority of fevers in children.
- Bacterial infections are also a frequent cause of fever.
- Non-infectious causes like inflammatory conditions, heatstroke, and certain medications can also lead to fever.
What is a Fever?
A fever, also known as pyrexia, is a temporary increase in your body temperature. It's a common symptom, not an illness itself, and often indicates that your body is fighting off an infection or disease. The average human body temperature is around 98.6°F (37°C), but this can fluctuate slightly throughout the day and vary from person to person. A temperature of 100.4°F (38°C) or higher is generally considered a fever.
Why Does the Body Develop a Fever?
The primary reason your body develops a fever is as a defense mechanism against pathogens. When your body detects harmful invaders like viruses, bacteria, fungi, or other microorganisms, your immune system releases signaling molecules called pyrogens. These pyrogens travel to the hypothalamus, a region in your brain that acts as your body's thermostat. The hypothalamus then signals your body to increase its temperature.
This elevated temperature is thought to have several benefits:
- Inhibits Pathogen Growth: Many viruses and bacteria reproduce best at normal body temperature. A higher temperature can slow down or stop their replication, giving your immune system a better chance to fight them off.
- Enhances Immune Response: A fever can stimulate the production and activity of white blood cells, which are crucial for fighting infections. It can also make the immune system more effective at recognizing and destroying infected cells.
- Speeds Up Repair: Some research suggests that a higher body temperature can accelerate the repair processes within the body.
Common Causes of Fever
The vast majority of fevers are caused by infections. Here are some of the most frequent culprits:
Infectious Causes:
- Viral Infections: These are the most common cause of fever, especially in children. Examples include the common cold, influenza (flu), COVID-19, chickenpox, measles, and gastroenteritis (stomach flu).
- Bacterial Infections: Bacteria can cause a wide range of infections leading to fever, such as strep throat, pneumonia, urinary tract infections (UTIs), ear infections, and meningitis.
- Fungal Infections: Less common than viral or bacterial infections, but can occur, especially in individuals with weakened immune systems. Examples include candidiasis or histoplasmosis.
- Parasitic Infections: Infections like malaria are caused by parasites and can lead to high fevers.
Non-Infectious Causes:
While infections are the leading cause, fevers can also arise from other conditions:
- Inflammatory Conditions: Autoimmune diseases like rheumatoid arthritis or lupus, and inflammatory bowel disease (IBD) can cause a low-grade fever as the body's immune system attacks its own tissues.
- Heatstroke: When the body overheats due to prolonged exposure to high temperatures or strenuous physical activity in hot weather, it can lead to heatstroke, a serious condition characterized by a very high body temperature.
- Certain Medications: Some drugs can cause a drug fever as an allergic reaction or a side effect. This can include certain antibiotics, anticonvulsants, and cardiovascular drugs.
- Vaccinations: It is common for children and adults to develop a mild, short-lived fever after receiving a vaccine. This is a normal immune response and a sign that the vaccine is working.
- Teething: While often blamed, teething in infants typically causes only a very slight rise in temperature, not a true fever. High fevers in infants are usually due to an underlying illness.
- Cancer: In some cases, certain cancers, particularly those affecting the blood or lymphatic system (like leukemia or lymphoma), can cause persistent fevers.
When to Seek Medical Advice
While most fevers are harmless and resolve on their own, it's important to know when to consult a healthcare professional. Seek medical advice if:
- The fever is very high (e.g., over 103°F or 39.4°C for adults, or specific guidelines for infants and children).
- The fever lasts for more than a few days (typically 2-3 days for adults, shorter for infants).
- The fever is accompanied by severe symptoms such as a stiff neck, severe headache, rash, difficulty breathing, persistent vomiting, or confusion.
- You have underlying health conditions that make you more vulnerable to complications.
- It's a baby under 3 months old with any fever.
Understanding the causes of fever can help you manage it effectively and know when to seek professional medical help.
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Sources
- Fever - WikipediaCC-BY-SA-4.0
- Fever in adults - NHSfair-use
- Fever - Symptoms and causes - Mayo Clinicfair-use
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