What causes syphilis

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Last updated: April 4, 2026

Quick Answer: Syphilis is caused by a bacterium called *Treponema pallidum*. This bacterium is primarily spread through direct contact with a syphilis sore, known as a chancre, during sexual activity.

Key Facts

What Causes Syphilis?

Syphilis is a sexually transmitted infection (STI) that is caused by a specific type of bacterium known as Treponema pallidum. This microscopic organism is spiral-shaped and thrives in warm, moist environments, making the human body its ideal habitat. The transmission of syphilis is almost exclusively through direct physical contact with an open syphilis sore, or chancre. These sores are typically painless, especially in the early stages, which can make them go unnoticed.

How Syphilis Spreads

The primary mode of transmission for syphilis is through sexual contact. This includes vaginal, anal, and oral sex. When an infected person comes into direct contact with the mucous membranes or skin of an uninfected person, the bacterium can enter the body.

It is important to note that syphilis cannot be spread through casual contact such as hugging, kissing, dancing, or sharing toilets, eating utensils, or clothing. The bacterium is fragile and cannot survive for long outside the human body.

Congenital Syphilis

Syphilis can also be transmitted from an infected pregnant person to their fetus during pregnancy or during childbirth. This is known as congenital syphilis. If left untreated, congenital syphilis can lead to serious health problems for the baby, including premature birth, stillbirth, low birth weight, and lifelong health issues such as developmental delays, blindness, deafness, and even death.

The Stages of Syphilis

Syphilis progresses through several stages if left untreated, and each stage is characterized by different symptoms and potential for transmission:

Diagnosis and Treatment

Syphilis is diagnosed through a physical examination and laboratory tests, including blood tests and examination of fluid from a chancre. Fortunately, syphilis is curable with antibiotics, most commonly penicillin. The effectiveness of treatment depends on the stage of the infection. Early stages are generally easier to treat and have a higher chance of complete recovery. It is crucial to seek medical attention if you suspect you have syphilis or have been exposed to someone with the infection.

Prevention

The most effective way to prevent syphilis is to practice safe sex. This includes using condoms consistently and correctly during vaginal, anal, and oral sex. Regular STI testing, especially if you have multiple partners or engage in high-risk sexual behaviors, is also essential for early detection and treatment.

Sources

  1. Syphilis - CDCfair-use
  2. Syphilis - WHOfair-use
  3. Syphilis - WikipediaCC-BY-SA-4.0

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